R6 ducting can be made from a variety of materials, including aluminum, galvanized steel, stainless steel, and fiberglass-lined ductboard. The selection of material often depends on the specific application requirements and environmental conditions in which the ducting will be used.

In general, R6 ducting is commonly made of fiberglass due to its lightweight properties and design that allow it to fit between wall studs and ceiling joists. It is versatile and can be installed in various configurations to suit different spaces. Additionally, R6 ducting is available with or without facings such as paper or foil-backed kraft, which can provide additional protection or performance features depending on the specific needs of the HVAC system.